Validating the performance of LC capillary columns
Biotech Fluidics reports that renowned experts in liquid chromatography, Dr.Maisch HPLC GmbH, has installed a Biotech Liquid Micro Flow Meter in its testing set-up to validate the performance of all capillary columns it manufactures.
Based in the Southwest of Germany, Dr.Maisch (dr-maisch.com) has over the last 45 years earned a reputation as a leading developer of high-quality standard and specialist capillary columns for HPLC and UHPLC. The company’s aim is to provide customers with its own specially developed phases to cope with the increasing demand for new HPLC-columns to solve routine and the most demanding separations.
In liquid chromatography, the flow rate is an essential parameter of the fluidic system running through a capillary column, as it affects retention time and efficiency. To guarantee high customer satisfaction, Dr.Maisch tests every column they manufacture in order to ensure that they are well packed and meet tight performance specifications. However, measuring the flow rate, especially at extremely low flow rates delivered by capillary systems, can be challenging.
With this reliable device we can validate that our test system for produced capillary columns is running at the correct flow rate.
CEO of Dr.Maisch HPLC GmbH, Dr. Johannes Maisch, explained “To have close control of our capillary testing procedure we installed a Biotech Liquid Micro Flow Meter in our chromatographic test system. With this reliable device we can validate that our test system for produced capillary columns is running at the correct flow rate. Using the Liquid Micro Flow Meter, we can now monitor the flow rate continuously, and with full system control can validate our performance testing of individual capillary columns. We have also found that inline solvent degassing using a Biotech Degasser is another important part of keeping the system performance at the highest level.”
The Liquid Micro Flow Meter from Biotech Fluidics is designed to continuously monitor ultralow fluidic flows in real time. Made to operate over the 100 nl to 80 µL/minute flow range with a resolution of one nl/minute. This device can be used for monitoring the consistency of capillary HPLC, UHPLC, LC/MS, high-precision flow cytometry and micro- & nanoscale fluidics applications. The meter uses a high-resolution thermal flow sensor that is accurate and sensitive and is compatible with almost any solvent without being invasive.
Discover more possibilities with the Liquid Micro Flow Meter at its products pages, or contact Biotech Fluidics to discuss your requirements in fluidic systems.
